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Schiff base was prepared by the condensation of 3-aminophenol and benzaldehyde in a 1:1 ratio and its complexes of Mn(II), Co(II) and Cu(II) were synthesized in a 1:2 ratio (Metal: Ligand) and the Schiff base and the complexes were characterized by using the different techniques. The infrared spectral data revealed that the Schiff base behaved as a bidentate ligand and the molar conductivity value indicated that the complexes were non-electrolytes. Furthermore, the in vitro antibacterial activity of the Schiff base and its complexes was evaluated against one gram-negative and one gram-positive bacteria to indicate that Mn (II) complex demonstrated a good broad-spectrum activity against all the tested bacterial strains.
Singh BK. Spectroscopic characterization and biological activity of Zn(II), Cd(II), Sn(II) and Pb(II) complexes with schiff base derived from Pyrrole-2-carboxaldehye and 2-amino phenol. Polyhedron. 2009;76:376-383.
Albada H, Prochnow B, Bobersky P, Bandow S, Metzler J. Highly active antibacterial ferrocenoylated or rutheno-cenoylated Arg-Trp peptides can be discovered by an L-to-D substitution scan. Chem. Sci.2014;5:4453–4459.
Kumar S, Dhar D, Saxena P. Applications of metal complexes of schiff bases. A Review. Journal of Scientific and Industrial Research. 2009;68:181-187.
Warra A. Transition metal complexes and their application in drugs and cosmetics. Journal of Chemical and Pharmaceutical Research. 2011;3(4):951-958.
Sangeeta VC, Sudhir SS, Ramesh SY. Synthesis and characterization of novel transition metal complexes of benzo-pyranone derivatives and their biological activities. Asian J. Research Chem. 2011; 4(5):834-837.
Neelima M, Kavitan P, Dinesh K. An overview of biological aspects of schiff base metal complexes. International Journal of Advancements in Research & Technology. 2013;2:52-66.
Juvansinh J, Jadeja, Mitesh B, Gondaliya DM. Synthesis, spectral characterization and biological activity studies of Schiff’s base of 1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-4-amine and its metal complexes. World Scientific News. 2016; 47(2):123-150.
Liu YT, Sheng J, Yin DW, Xin H, Yang XM, Qiao QY. Ferrocenyl chalcone-based Schiff bases and their metal complexes: Highly efficient, solvent-free synthesis, characterization. Biological Research Journal of Organometallic Chemistry. 2018; 27-33.
Spange S, Vilsmeier E, Adolph S, Fährmann A. Unusual Solvatoch- romism of the 4,4’-bis(dimethylamino) benzo-phenone (Michler’s ketone)-Tetracyanoe-thylene electron donor-acceptor Complex. Journal of Physical Organic Chemistry. 1999;12:547-556.
Ndahi N, Pindiga Y, Sandabe U. Synthesis, characterization & antibacterial studies of some schiff base Complexes of Cobalt(II), Nickel (II) and Zinc(II). Asian Journal of Biochemical and Pharmaceutical Research. 2012;2:308-316.
Tumer M, Koksal H, Serin S, Digrak M. Antimicrobial activity studies of mononuclear and binuclear mixed-ligand copper (II) complexes derived from schiff base ligands and 1,10-Phenanthroline. Transition Metal Chemistry. 1999;24:13-17.
Rehman W, Baloch M, Badshah A.Synthesis, spectral characterization and bio-analysis of some organotin(IV) complexes. European Journal of Medicinal Chemistry. 2008;43:2380-2385.
Alyaa AA. Synthesis and antibacterial studies of metal complexes of Cu(II), Ni(II) and Co(II) with tetradentate ligand. Journal of Biophysical Chemistry. 20107;8:13- 21.
Archana S. Synthesis and characterization of schiff base salicylaldehyde and thiohydrazones and its metal complexes. Advances in Applied Science Research. 2013;4(4):152-154.
Geary WJ. The use of conductivity measurements in organic solvents for the characterization of coordination compounds. Coordination Chemical Review. 1971;7:81-122.
Sabry A, Saad R, El-Dine A, Abdel-Hady M. Synthesis, characterization and anti-microbial activity of Schiff base (E)-N-(4-2-hydroxybenzylideneamino) phenylsulfonyl) acetamide metal complexes. American Journal of Analytical Chemistry. 2016;7: 233-245.
Bharat A, Pratik N, Pratik B. Synthesis of schiff base and their transition metal complexes, characterization and applica-tion. International Journal of Science, Technology and Management. 2015;4(1): 642-652.
Pratibha M, Sunil J, Vatsala P. Biologically active Co (II), Ni (II), Cu (II) and Mn(II) Complexes of schiff bases derived from vinyl aniline and heterocyclic aldehydes. International Journal of ChemTech Research. 2009;1(2):225-232.
Selwin R, Joseyphus Shiju C, Joseph J, Justin CD. Synthesis and characterization of Schiff Base Metal Complexes Derived from Imidazole-2-carboxaldehyde with L-phenylalanine. Scholars Research Library. 2015;7(6):265-270.
Mohammad MY, Kuddushi M, Abrar HM, Vinod LP, Mihir SP, Roma KP. Synthesis and characterization of Schiff base aniline with 5-bromo-2-hydroxylbenzaldehyde and their metal complexes. International Journal of Recent Scientific Research. 2018;9:26026-26030.
Viswanathamurth P, Karvembu R, Tharaneeswaran V, Kanatarajan K. Ruthenium(II) complexes containing bidentate Schiff bases and triphenyl phosphine Indian Academy of Sciences. 2005;3:235-238.
Tweedy BG. Plant extracts with metal Ions as potential antimicrobial agents. Phytopatology. 1964;55:910-918.