New Synthetic Pathways for Thiocarbohydrazide and Salicylaldehyde Azine Compounds

Main Article Content

Solomon Omwoma Lugasi

Abstract

Thiocarbohydrazide synthesis is an important intermediate step for many hydrazine organic synthetic reactions. Synthesis of thiocarbohydrazide can be done by reaction of carbon disulfide with hydrazine (hydrazinolysis) in water at 0°C giving 25% yield (based on [hydrazine]). However, in this article, we achieve a 96% yield (based on [hydrazine]) by carrying out the reaction in methanol at 24°C. The thiocarbohydrazide is then used to synthesize 1,5-bis (2-hydroxybenzaldehyde) dithiocarbohydrazone. By refluxing the latter compound in pyridine at 80°C, it decomposes and rearranges to give salicylaldehyde azine.

Keywords:
Thiocarbohydrazide, salicylaldehyde azine, hydrazinolysis

Article Details

How to Cite
Omwoma Lugasi, S. (2017). New Synthetic Pathways for Thiocarbohydrazide and Salicylaldehyde Azine Compounds. Asian Journal of Chemical Sciences, 3(1), 1-8. https://doi.org/10.9734/AJOCS/2017/35504
Section
Original Research Article