Synthesis, Characterization, and Antimicrobial Activity Studies of New Schiff Base Tetradentate Ligands and Their Manganese (II) Complexes
Elham Abdalrahem Bin Selim
Department of Chemistry, Faculty of Science, Hadhramout University, Mukalla, Hadhramout, Yemen.
Mohammed Hadi Al–Douh *
Department of Chemistry, Faculty of Science, Hadhramout University, Mukalla, Hadhramout, Yemen.
Dahab Salim Al–Nohey
Department of Chemistry, Faculty of Science, Hadhramout University, Mukalla, Hadhramout, Yemen.
Wedad Mohammed Al–Haik
Department of Biology, Faculty of Science, Hadhramout University, Mukalla, Hadhramout, Yemen.
Khalid Saeed Sonbol
Alsalam Medical Center, Mukalla, Hadhramout, Yemen.
*Author to whom correspondence should be addressed.
Abstract
Two Schiff base tetradentate ligands 4 and 5 were synthesized by condensation reactions of 4-hydroxy-3-methoxy-5-((2-nitrophenyl)diazenyl) benzaldehyde 1 with 1,2-diaminoethane 2 and 1,2-diaminobenzene 3, respectively. Treatment of synthesized ligands with the manganese (II) chloride MnCl2 6 gave two complexes 7 and 8 of general formula ML. The synthesized ligands and their complexes were characterized by FTIR, UV-Vis, Mass spectroscopy, and elemental analysis. The biological activity of the synthesized compounds were tested. It was found that ligand 5 and the complexes 7 and 8 possess antibacterial activity against the gram –ve Proteus mirabilis.
Keywords: Synthesis, bis-Schiff bases, tetradentate complexes, FTIR, UV–VIS, Mass spectra, antimicrobial.