Synthesis, Characterization and Investigation of Antimicrobial Activity of a New Schiff Base, 2-(((2-((4-hydroxybenzylidene) amino)ethyl)imino)methyl) Phenol and Its Cu(II) and Ni(II) Complexes
Musarat Farjana Yesmin
Department of Chemistry, University of Rajshahi, Rajshahi, 6205, Bangladesh.
Farzana Khanm Camellia
Department of Chemistry, University of Rajshahi, Rajshahi, 6205, Bangladesh.
Modina Bashar
Department of Chemistry, University of Rajshahi, Rajshahi, 6205, Bangladesh.
Md. Sajjad Hossain
Department of Chemistry, University of Rajshahi, Rajshahi, 6205, Bangladesh.
Saiyad Nasira
Department of Chemistry, University of Rajshahi, Rajshahi, 6205, Bangladesh.
Nayon Uddin
Department of Chemistry, University of Rajshahi, Rajshahi, 6205, Bangladesh.
Md. Ashrafuzzaman
Department of Chemistry, University of Rajshahi, Rajshahi, 6205, Bangladesh.
Md. Yeamin Reza
Department of Chemistry, University of Rajshahi, Rajshahi, 6205, Bangladesh.
Md. Kudrat-E-Zahan
Department of Chemistry, University of Rajshahi, Rajshahi, 6205, Bangladesh.
Md. Masuqul Haque *
Department of Chemistry, University of Rajshahi, Rajshahi, 6205, Bangladesh.
Laila Arjuman Banu *
Department of Chemistry, University of Rajshahi, Rajshahi, 6205, Bangladesh.
*Author to whom correspondence should be addressed.
Abstract
New complexes of Cu (II) and Ni (II) of the Schiff Base, 2-(((2-((4-hydroxybenzylidene) amino)ethyl)imino)methyl) phenol were synthesized and characterized by analytical and physico-chemical techniques including magnetic susceptibility, conductivity measurements, electronic and IR spectral studies. The infrared spectral studies revealed the tetra-dentate nature of the Schiff base in the complexes. On the basis of all characterizations, square- planar geometry has proposed for all the obtained complexes. The complexes showed moderate antimicrobial activity against Escherichia coli and Staphylococcus aureus.
Keywords: Schiff base ligands, transition metals, salicylaldehyde, antibacterial activity