Synthesis, Characterization and Antibacterial Evaluation of Mn (II), Co (II) and Cu (II) Complexes of Schiff Base Derived from 3-aminophenol and Benzaldehyde
Usman Abubakar Adamu
Department of Chemistry, Gombe State University, P.M.B. 127, Gombe, Nigeria.
Buhari Magaji
Department of Chemistry, Gombe State University, P.M.B. 127, Gombe, Nigeria.
Muhammad Nazifi Ibrahim
Department of Chemistry, Gombe State University, P.M.B. 127, Gombe, Nigeria.
Mukhtar Muhammad Sani
Department of Chemistry, Gombe State University, P.M.B. 127, Gombe, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
Schiff base was prepared by the condensation of 3-aminophenol and benzaldehyde in a 1:1 ratio and its complexes of Mn(II), Co(II) and Cu(II) were synthesized in a 1:2 ratio (Metal: Ligand) and the Schiff base and the complexes were characterized by using the different techniques. The infrared spectral data revealed that the Schiff base behaved as a bidentate ligand and the molar conductivity value indicated that the complexes were non-electrolytes. Furthermore, the in vitro antibacterial activity of the Schiff base and its complexes was evaluated against one gram-negative and one gram-positive bacteria to indicate that Mn (II) complex demonstrated a good broad-spectrum activity against all the tested bacterial strains.
Keywords: Antibacterial activity, benzaldehyde, non-electrolyte, schiff base complexes, 3-aminophenol