Copper (II) Complex of Salicylaldehyde Semicarbazone: Synthesis, Characterization and Antibacterial Activity
Dipta Sarker
Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.
Md. Rabiul Karim
Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.
Md. Masuqul Haque
Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.
Rausan Zamir
Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.
Md. Ali Asraf *
Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.
*Author to whom correspondence should be addressed.
Abstract
Salicylaldehyde semicarbazone ligand and its Cu (II) complex have been synthesized and characterized by a range of physicochemical methods. Experimental data shows the complex is monomeric and the copper atom is four coordinated in a square planar geometry. The ligand chelates the copper in a tridentate fashion through the carbonyl O, imine N, and phenolato O with the fourth position being occupied by coordinated Cl. Antibacterial activity of the prepared compounds was tested against the microbes Enterobacter Aerogenes and Bacillus Cereus. The metal complex showed higher antibacterial activity than the free ligand.
Keywords: Antibacterial activity, complexation, semicarbazone, tridentate ligand.